Either you do not have the newest version of Adobe Flash®, or you have JavaScript disabled.

Please ensure you have these capabilities.

Research


2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008

2008 Publications

Incidental detection of an occult oral malignancy with autofluorescence imaging: a case report
Nadarajah Vigneswaran, Sheila Koh and Ann Gillenwater; Head & Neck Oncology 2009, 1:37

The impact of inaccurate internet health information in a secondary school learning environment
- Kortum P, Edwards C, Richards-Kortum R; J Med Internet Res 2008, 10(2):e17

Low-cost, multimodal, portable screening system for early detection of oral cancer
- Rahman M, Chaturvedi P, Gillenwater AM, Rebecca Richards-Kortum; J Biomed Opt., 13(3):0305020, May-June 2008

Metal-based nanorods as molecule-specfic contrast agents for reflectance imaging in 3D tissues
- Javier D, Nitin N, Roblyer D, Richards-Kortum R; J of Nanophotonics, Vol. 2, 023506, Apr 2008

Autofluorescence and diffuse reflectance spectroscopy of oral epithelial tissue using a depth-sensitive fiber-optic probe
- Schwarz R, Gao W, Daye D, Williams M, Richards-Kortum R, Gillenwater A; Applied Optics, 47(6): 825-834, Feb 2008

Aptamer-targeted gold nanoparticles as a molecular-specific contrast agents for reflectance imaging
- Javier, D, Nitin N, Levy M, Ellington A, Richards-Kortum R; Bioconjugate Chem., 19, 1309-1312, 2008

Automated image analysis of digital colposcopy for the detection of cervical neoplasia
- Park S, Follen M, Milbourne A, Rhodes H, Malpica A, MacKinnon N, MacAulay C, Markey M, Richards-Kortum R; J Biomed Opt., 13(1):014029, Jan-Feb 2008

In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope
- Maitland K, Gillenwater A, Williams M, El-Naggar A, Descour M, Richards-Kortum R; Oral Oncol., 10.1016, Feb 2008

2007 Publications

Oligonucleotide-coated metallic nanoparticles as a flexible platform for molecular imaging agents
- Nitin N, Javier DJ, Richards-Kortum R; Bioconjug Chem., Oct. 2007

Dual-mode reflectance and fluorescence near-video-rate confocal microscope for architectural, morphological and molecular imaging of tissue
- Carlson AL, Coghlan LG, Gillenwater AM, Richards-Kortum RR; J Microsc., 228(Pt 1): 11-24, Oct. 2007

Confocal microscopy and molecular-specific optical contrast agents for the detection of oral neoplasia
- Carlson AL, Gillenwater AM, Williams MD, El-Nagger AK, Richards-Kortum; Technol Cancer Res Treat, 6(5):361-74, Oct. 2007

Fluorescence and reflectance device variability throughout the progression of a phase II clinical trial to detect and screen for cervical neoplasia using a fiber optic probe
- Freeberg JA, Serachitopol DM, McKinnon N, Price R, Atkinson EN, Cox DD, MacAulay C, Richards-Kortum R, Follen M, Pikkula B; J Biomed Opt., 12(3):034015, May-Jun 2007

Instrumentation as a source of variability in the application of fluorescence spectroscopic devices for detecting cervical neoplasia
- Pikkula BM, Shuhatovich O, Price RL, Serachitopol DM, Follen M, McKinnon N, MacAulay C, Richards-Kortum R, Lee JS, Atkinson EN, Cox DD; J Biomed Opt., 12(3):034014, May-Jun 2007

Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivo
- Aaron J, Nitin N, Travis K, Kumar S, Collier T, Park SY, Jose-Yacaman M, Coghlan L, Follen M, Richards-Kortum R, Sokolov K; J Biomed Opt., 12(3):034007, May-Jun 2007

Real-time reflectance confocal microscopy: comparison of two-dimensional images and three-dimensional image stacks for detection of cervical precancer
- Collier T, Guillaud M, Follen M, Malpica A, Richards-Kortum R; J Biomed Oct., 12(2):024021, Mar-Apr 2007

A translational bioengineering course provides substantial gains in civic scientific literacy
- Richards-Kortum R, Buckley D, Schwarz RA, Atkinson EN, Follen M; Ann Biomed Eng, 35(8):1324-32, Apr 2007

Plasmonic nanosensors for imaging intracellular biomarkers in live cells
- Kumar S, Harrison N, Richards-Kortum R, Sokolov K; Nano Lett., 7(5)1338-43, Apr 2007

Light scattering from collagen fiber networks: micro-optical properties of normal and neoplastic stroma
- Arifler D, Pavlova I, Gillenwater A, Richards-Kortum R; Biophys J., 92(9):3260-74, Feb 2007

Molecular optical imaging of therapeutic targets of cancer
- Sokolov K, Nida D, Descour M, Lacy A, Levy M, Hall B, Dharmawardhane S, Ellington A, Korgel B, Richards-Kortum R; Adv Cancer Res., 96:299-344, 2007

2005 Publications

An Image Model and Segmentation Algorithm for Reflectance Confocal Images of In Vivo Cervical Tissue
- Kortum RR; IEEE Transactions on Image Processing, Volume 14, Issue 9, Page(s):1265 - 1276, Sept. 2005.

Ball lens coupled fiber-optic probe for depth-resolved spectroscopy of epithelial tissue
- Schwarz RA, Arifler D, Chang SK, Pavlova I, Hussain IA, Mack V, Knight B, Richards-Kortum R, Gillenwater AM; Optics Letters, 30(10): 1159-1161, May 2005.

Combined reflectance and fluorescence spectroscopy for in vivo detection of cervical pre-cancer
- Chang SK, Mirabal YN, Atkinson EN, Cox D, Malpica A, Follen M, Richards-Kortum R; J Biomed Opt., 10(2):024031, Mar-Apr 2005.

In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens
- Carlson K, Chidley M, Sung KB, Descour M, Gillenwater A, Follen M, Richards-Kortum R; Applied Optics, 44(10): 1792-1797, Apr 2005.

Multispectral digital microscopy for in vivo detection of oral neoplasia in the hamster cheek pouch model of carcinogenesis
- Park SY, Sokolov K, Collier T, Aaron J, Markey M, Mackinnon N, MacAulay C, Coghlan L, Milbourne A, Follen M, Richards-Kortum R; Optics Express, 13:749-762, Feb 2005.

Reflectance spectroscopy for diagnosis of epithelial precancer: model-based analysis of fiber-optic probe designs to resolve spectral information from epithelium and stroma
- Arifler D, Schwarz RA, Chang SK, Richards-Kortum R; Applied Optics, Volume 44, Issue 20, 4291-4305, July 2005.

Sources of scattering in cervical tissue: determination of the scattering coefficient by confocal microscopy
- Collier T, Follen M, Malpica A, Richards-Kortum R; Applied Optics, 44(11): 2072-2081, Apr 2005.

2004 Publications

A Far-red Fluorescent Contrast Agent to Image Epidermal Growth Factor Receptor Expression
- Hsu E, Anslyn E, Dharmawardhane S, Alizadeh-Naderi R, Aaron J, Sokolov K, El-Naggar A, Gillenwater A, Richards-Kortum R; Photochemistry and Photobiology, 79(3): 272-279, 2004.

A pilot study for a screening trial of cervical fluorescence spectroscopy
- Nath, A., Rivoire, K., Chang, S., West, L., Cantor, S. B., Basen-Engquist, K., Adler-Storthz, K., Cox, D. D., Atkinson, E. N., Staerkel, G., Macaulay, C., Richards-Kortum, R., Follen, M.; International Journal of Gynecological Cancer, 14(6): 1097-1108, Nov 2004.

Ahh...The Power of Guilt
- Richards-Kortum R; SWE Magazine, Winter, 2004, pp 81-82.

Analytical Model to Describe Fluorescence Spectra of Normal and Preneoplastic Epithelial Tissue: Comparison with Monte Carlo Simulations and Clinical Measurements
- Chang SK, Arifler D, Drezek R, Follen M, Richards-Kortum R; Journal of Biomedical Optics, 9(3): 511-522, May/June 2004.

Confocal Microscopy for Detection of Precancerous Cervical Lesions
- Luck B, Carlson K, Collier T, Sung KB; IEEE Potentials, February 2004.

Detection and Diagnosis of Oral Neoplasia with an Optical Coherence Microscope
- Clark A. L., Gillenwater A., Alizadeh-Naderi R.,El-Naggar A. K., Richards-Kortum R.; Journal of Biomedical Optics 9(6):1271-1280, Nov/Dec 2004.

Effect of Probe Pressure on Cervical Fluorescence Spectroscopy Measurements
- Nath A., Rivoire K., Chang S., Cox D., Atkinson E. N., Follen M., Richards-Kortum R.; Journal of Biomedical Optics, 9(3): 523-533, May/June 2004.

High Resolution Reflectance Imaging in Optically Dense Tissue Phantoms with Structured-Illumination
- Tkaczyk T, Rahmann M, Mack V, Sokolov K, Rogers J, Richards-Kortum R, Descour M; Optics Express, 12(16): 3745-3758, Aug 2004.

In vivo pathology: microendoscopy as a new endoscopic imaging modality
- MacAulay C., Lane P., Richards-Kortum R.; Gastrointestinal Endoscopy Clinics of North America. 14(3): 595-620, xi, 2004.

The Effects of Repeated Spectroscopic Pressure Measurements on Fluorescence Intensity in the Cervix
- Rivoire K, Nath A, Cox D, Atkinson EN, Richards-Kortum R, Follen M; American Journal of Obstetrics and Gynecology, 191(5):1606-1617, 2004.

Vision Enhancement System for Detection of Oral Cavity Neoplasia based on Autofluorescence
- Svistun E, Alizadeh-Naderi R, El-Naggar A, Jacob R, Gillenwater A, Richards-Kortum R; Head & Neck, 26(3):205-15, 2004.

2003 Publications

Anatomical and Biochemical Origins of Normal and Precancerous Cervical Autofluorescence Using Laser Scanning Fluorescence Confocal Microscopy
- Pavlova I, Sokolov K, Drezek R, Malpica A, Follen M, and Richards-Kortum R; Photochemistry and Photobiology, 77(5):550-5, 2003.

Cervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers
- Follen M, Meyskens FL Jr, Alvarez RD, Walker JL, Bell MC, Storthz KA, Sastry J, Roy K, Richards-Kortum R, Cornelison TL. Cancer. 98 (9 Suppl):2044-51, 2003 Nov 1.

Confocal Microscopy for Real Time Detection of Oral Cavity Neoplasia
- Clark AL, Gillenwater A, Collier T, Alizadeh-Naderia R, El-Naggar A, Richards-Kortum R; Clinical Cancer Research, 9(13):4714-4721, 2003.

Detecting a signal from the menstrual cycle in fluorescence spectroscopy of the cervix
- Cox D, Chang SK, Dawood MY, Staerkel G, Utzinger U, Richards-Kortum R, and Follen M; Journal of Applied Spectroscopy,57:67-72, 2003

Determination of Epithelial Tissue Scattering Coefficient using Confocal Microscopy
- Collier T, Arifler D, Malpica A, Follen M, Richards-Kortum R; IEEE Journal of Quantum Electronics, 9(2): 307-313, 2003.

Effects of Biographical Variables on Cervical Fluorescence Emission Spectra
- Brookner C, Utzinger U, Follen M, Richards-Kortum R, and Atkinson EN; Journal of Biomedical Optics, 8:479-83, 2003.

Fiber optic confocal reflectance microscopy: a new real-time technique to view nuclear morphology in cervical squamous epithelium in vivo
- Sung KB, Liang C, Descour M, Follen M, Malpica A, Richards-Kortum R; 11(24):3171-3181, Optics Express, 2003.

Fiber optic probes for biomedical optical spectroscopy
- Utzinger U, Richards-Kortum R; Journal of Biomedical Optics, 8(1):121-147, 2003.

Formative and Summative Assessment of the IGERT Program in Optical Biomolecular Bio-Engineering at UT Austin
- Richards-Kortum R, Dailey M, Harris C; Journal of Engineering Education, 92(4):345-350, 2003.

Imaging Quality Assessment of Multi-modal Miniature Microscope
- Lee J, Rogers JD, Descour MR, Hsu E, Aaron JS, Sokolov K, and Richards-Kortum R; Optics Express, Vol. 11:1436 - 1451, 2003.

Light scattering from cervical cells throughout neoplastic progression: influence of nuclear morphology, DNA content, and chromatin texture
- Drezek R, Guillaud M, Collier T, Boiko I, Malpica A, Macaulay C, Follen M, Richards-Kortum R; Journal of Biomedical Optics, 8(1):7-16, 2003

Light Scattering from Normal and Dysplastic Cervical Cells at Different Epithelial Depths: Finite Difference Time Domain Modeling with a Perfectly Matched Layer Boundary Condition
- Arifler D, Guillaud M, Carraro A, Malpica A, Follen M, Richards-Kortum R; Journal of Biomedical Optics, 8:484-494, 2003.

Multispectral Digital Colposcopy for in vivo Detection of Cervical Cancer
- Benavides JM, Chang S, Park SY, MacKinnon N, MacAulay C, Milbourne A, Malpica A, Follen M, and Richards-Kortum R; Optics Express, 11:1223-36, 2003

Optical Imaging for the Detection of Cervical Precancers In Vivo
- Drezek R, Faupel M, Pitris C, Feld M, Brewer M, Richards-Kortum R, and Follen M; Cancer - Supplement, 98/9:2015-2027, 2003

Optical Systems for In Vivo Molecular Imaging of Cancer
- Sokolov K, Aaron J, Hsu B, Nida D, Gillenwater A, Follen M, MacAulay C, Adler-Storthz K, KOrgel B, Descour M, Pasqualini R, Arap W, Lam A, Richards-Kortum R; Technology in Cancer Research and Treatment, 2(5):491-504, 2003.

Optimal Visual Perception and Detection of Oral Cavity Neoplasia
- Utzinger U, Bueeler M, Oh S, Heintzelman D.L. Svistun E, Abd-El-Barr M, Gillenwater A, and Richards-Kortum R; IEEE Trans Biomed Eng, 50(3):396-9, 2003.

Patient Distress and Satisfaction Associated with Optical Spectroscopy of the Cervix
- Basen-Engquist K, Shinn EH, Warneke C, de Moor C, Le T, Richards-Kortum R, and Follen M;Am J Obstet Gynecol. 2003 Oct;189(4):1136-42

Real-Time Vital Optical Imaging of Precancer Using Anti-Epidermal Growth Factor Receptor Antibodies Conjugated to Gold Nanoparticles
- Sokolov K., Follen M., Aaron J., Pavlova I., Malpica A., Lotan R., and Richards-Kortum R.; Cancer Research, 63:1999-2004, May 1, 2003.

Relationship Between Collagen Autofluorescence of the Human Cervix and Menopausal Status
- Gill E, Malpica A, Alford R, Nath AR, Follen M, Richards-Kortum R, and Ramanujam N; Photochemistry and Photobiology, 77:653-658, 2003

2002 Publications

Contrast agents for confocal microscopy: how simple chemicals affect confocal images of normal and cancer cells in suspension
- Zuluaga AF, Drezek R, Collier T, Lotan R, Follen M, and Richards-Kortum R; The Journal of Biomedical Optics, 7:398-403, 2002.

Design of a high-numerical-aperature miniature microscope objective for endoscopic fiber confocal reflectance microscope
- Liang C, Sung KB, Richards-Kortum R, and Descour MR; Applied Optics, 41:4603-4610, 2002.

Endoscopic Microscopy
- Sokolov K, Sung KB, Collier T, Clark A, Arifler D, Lacy A, Descour M, Richards-Kortum R; Disease Markers, 18(5,6): 269-292, 2002.

Fiber optic probe for polarized reflectance spectroscopy in vivo: Design and performance
- Myakov A, Nieman L, Wicky L, Utzinger U, Richards-Kortum R, and Sokolov K; Journal of Biomedical Optics, 7(3):388-97, 2002.

Fiber-Optic Confocal Reflectance Microscope with Miniature Objective for In Vivo Imaging of Human Tissues
- Sung K, Liang C, Descour M, Collier T, Follen M, and Richards-Kortum R; IEEE Trans BME, 49:1168-1172, 2002.

Fluorescence spectroscopy as biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents
- Brewer M, Utzinger U, Yang L, Atkinson EN, Satterfield W, Auersperg N, Richards-Kortum R, Follen M, and Bast R; Journal of Biomedical Optics, 7:20-26, 2002.

Fluorescence Spectroscopy for Cervical Pre-Cancer Detection: Is There Variance Across the Menstrual Cycle?
- Chang SK, Dawood MY, Staerkel G, Utzinger U, Richards-Kortum R, and Follen M; Journal of Biomedical Optics, in press, 2002.

Near Real Time Confocal Microscopy of Amelanotic Tissue: Detection of Dysplasia in Ex-Vivo Cervical Tissue
- Collier T, Lacy A, Malpica A, Follen M, and Richards-Kortum R; Academic Radiology, 9:504-512, 2002.

Near real time in vivo fiber optic confocal microscopy: sub-cellular structure resolved
- Sung KB, Liang C, Descour M, Collier T, Follen M, and Richards-Kortum R; J Micros, 207(2):137-145, 2002.

Near real-time in vivo confocal imaging of mouse mammary tumors
- Lacy AA, Collier T, Price JE, Dharmawardhane S, and Richards-Kortum R; Frontiers in Bioscience. 7. January 2002. f1-7.

Optical spectroscopy for detection of neoplasia
- Sokolov K, Follen M, and Richards-Kortum R; Current Opinion in Chemical Biology 6:651-658, 2002.

Optimal Excitation Wavelengths for Discrimination of Cervical Neoplasia
- Chang SK, Follen M, Malpica A, Utzinger U, Staerkel G, Cox D, Atkinson EN, MacAulay C, and Richards-Kortum R; IEEE Trans BME, 49(10):1102-1111, 2002.

Realistic three-dimensional epithelial tissue phantoms for biomedical optics
- Sokolov K, Galvan J, Myakov A, Lacy A, Lotan R, and Richards-Kortum R; The Journal of Biomedical Optics, 7:148-156, 2002.

Reflectance spectroscopy for in vivo detection of cervical precancer
- Mirabal YN, Chang SK, Atkinson EN, Malpica A, Follen M, and Richards-Kortum R; Journal of Biomedical Optics 7(4):587-594, 2002.

Towards the development of miniaturized imaging systems for detection of pre-cancer
- Descour MR, Karkkainen AHO, Rogers JD, Liang C, Kilic B, Madenci E, Rantala JT, Weinstein RS, Richards-Kortum RR, Anslyn EV, and Dupuis RD; IEEE Journal of Quantum Electronics 38:122-130, 2002.

Variation of Fluorescence Spectroscopy during the Menstrual Cycle
- MacAulay C, Richards-Kortum R, Atkinson EN, Cox D, and Follen M; submitted to Optics Express, 2002.

2001 Publications

Autofluorescence Microscopy of Fresh Cervical-Tissue Sections Reveals Alterations in Tissue Biochemistry with Dysplasia
- Drezek R, Brookner C, Pavlova I, Boiko I, Malpica A, Lotan R, Follen M, and Richards-Kortum R; Photochemistry and Photobiology, 73(6):636-41, 2001.

Biomarker Modulation in a Nonhuman Rhesus Primate Model for Ovarian Cancer Chemoprevention
- Brewer M, Utzinger U, Satterfield W, Gershensen D, Bast R, Richards-Kortum R, and Follen M; Cancer Epidemiology, Biomakers & Prevention, 10(8):889-93, 2001.

Fast and Noninvasive Fluorescence Imaging of Biologic Tissues In Vivo Using a Flying-Spot Scanner
- Ramanujam N, Chen J, Gossage K, Richards-Kortum R, and Chance B; IEEE Transactions on Biomedical Engineering, 48(9):1034-,1041 2001.

Fiber confocal reflectance microscope (FCRM) for in-vivo imaging
- Liang C, Sung K, Richards-Kortum R, and Descour MR; Optics Express, 9(13):821-830, 2001.

Fluorescence Spectroscopy for In Vivo Characterization of Ovarian Tissue
- Brewer M, Utzinger U, Silva E, Gershenson D, Bast RC, Follen M, and Richards-Kortum R; Lasers in Surgery and Medicine, 29:128-135, 2001.

Fluorescence Spectroscopy of Epithelial Tissue Throughout the Dysplasia-Carcinoma Sequence in an Animal Model: Spectroscopic Changes Precede Morphologic Changes
- Coghlan L, Utzinger U, Richards-Kortum R, Brookner C, Zuluaga A, Gimeniz-Conti I, Follen M; Lasers in Surgery and Medicine 29:1-10, 2001.

Low temperature fluorescence imaging of freeze-trapped human cervical tissues
- Ramanujam N, Richards-Kortum R, Thomsen S, Mahadevan-Jansen A, Follen M, and Chance B; Optics Express. Vol. 8, No. 6, 335-343, 2001

Near real time in vivo fiber optic confocal microscopy: sub-cellular structure resolved
- Sung KB, Liang C, Descour M, Collier T, Follen M, and Richards-Kortum R; Journal of Microscopy, 207(2):137-145, 2001.

Near Real-Time Confocal Microscopy of Amelanotic Tissue: Detection of Dysplasia in ex Vivo Cervical Tissue
- Collier T, Lacy A, Malpica A, Follen M, and Richards-Kortum R; Academic Radiology, 9:504-512, 2001.

Near Real-Time In Vivo Confocal Imaging of Mouse Mammary Tumors
- Lacy Alicia A, Collier Tom, Price Janet E, Dharmawardhane Su, and Richards-Kortum Rebecca.

Near-Infrared Raman Spectroscopy for in Vivo Detection of Cervical Precancers
- Utzinger U, Heintzelman DL, Mahadevan-Jansen A, Malpica A, Follen M, and Richards-Kortum R; Applied Spectroscopy, 55(8):955-959, 2001.

Reflectance Spectroscopy for In Vivo Characterization of Ovarian Tissue
- Utzinger U, Brewer M, Silva E, Gershensen D, Bast R, Follen Mitchell M, and Richards-Kortum R; Lasers in Surgery and Medicine, Vol. 28, 56-66, 2001.

Understanding the Contributions of NADH and collagen to cervical tissue fluorescence spectra: Modeling, measurements, and implications
- Drezek R, Sokolov K, Utzinger U, Boiko I, Malpica A, Follen M, and Richards-Kortum R; Journal Biomedical Optics, 6(4): 385-396, 2001.